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KMID : 1151820200140050585
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Journal of the Korean Society of Radiology
2020 Volume.14 No. 5 p.585 ~ p.595
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Comparison of Differences in Subcortical between Men and Women in their Seventies
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Ahn Byung-Ju
Park Hye-Mi
Kim Joo-Yeon
Lee Jeong-Hwan
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Abstract
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Magnetic resonance imaging(MRI) has become an important technique for examining changes in human brain structure with neurological disorders. Brain development is a very complex process, and is affected by neurogenesiss and genetic programs. As age increases, structures of the brain change, which can contribute to the formation of brain diseases. Among the various factors, Gender is one of the greatest influential factors that affect the development of a healthy brain. The images were analyzed through various programs found in FSL such as SIENAX, FIRST, and Vertex analysis. Our results show that significant gender-related differences in subcortical areas were observed at the particular age group. The magnitude of these differences between gender and volume varied depending on the area investigated. In this study, we used more advanced 3T MRI for the structural analysis of subcortical structures between each gender. In addition, Vertex Analysis was used to visualize the volumetric differences in subcortical structures between each gender. This study is limited to groups in their 70s, therefore, further studies are needed for wider age groups.
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KEYWORD
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MRI, T1WI, Gender, Subcortical, FSL
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